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Persistent Antigen and Germinal Center B Cells Sustain T Follicular Helper Cell Responses and Phenotype

✍ Scribed by Baumjohann, Dirk; Preite, Silvia; Reboldi, Andrea; Ronchi, Francesca; Ansel, K. Mark; Lanzavecchia, Antonio; Sallusto, Federica

Book ID
120054197
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
728 KB
Volume
38
Category
Article
ISSN
1074-7613

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## Abstract Antibodies against bacterial capsular polysaccharides play a critical protective role. Responses to these antigens can occur without the help or control of T cells and are associated with marginal zone (MZ) B cells. Capsular antigens are diverse and some cross‐react with self‐carbohydra