Persistence of plasma cells in the kidneys of autoimmune NZB/W mice
✍ Scribed by G Cassese, S Lindenau, B de Boer, S Arce, A Hauser, G Riemekasten, C Berek…
- Book ID
- 120708978
- Publisher
- BioMed Central
- Year
- 2001
- Tongue
- English
- Weight
- 430 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1478-6354
- DOI
- 10.1186/ar226
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📜 SIMILAR VOLUMES
## Loss of suppressor T cells was demonstrated in NZB/W mice, an animal model of autoimmunity. As NZB/W mice matured they lost splenic T cells that could be activated by concanavalin A (Con A) to become sup pressor cells and lost the ability to produce the regulator of humoral immune responses, so
## Proliferation of Ly-1 B cells in autoimmune NZB and (NZB X NZW)F1 mice* Spontaneous autoimmune disease in NZB and (NZB x NZW)FI (B/W) mice is associated with a spectrum of lymphoproliferative abnormalities, but the relationship between autoimmunity and lymphoproliferation is poorly understood.