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Persistence of HIV-1 silent infection in seronegative subjects at high risk

✍ Scribed by Mario Pezzella; Maria A. Rosci; Michela Miceli; Nicoletta Vonesch; Elena Sturchio; Marina Mirolo; Emilio Mannella


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
502 KB
Volume
35
Category
Article
ISSN
0146-6615

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✦ Synopsis


Abstract

Twenty regular sexual partners of HIV‐1 infected subjects, without detectable human irnmunodeficiency virus (HIV‐1) antibody and positive for HIV‐1 genome by in situ hybridization (ISH), were selected and studied longitudinally for 6–36 months to estimate the duration of silent infection. During the follow‐up period, 10 showed atypical Western Blot (WB) patterns. Two seronegative partners seroconverted. Rapid progress t o AIDS was observed in 7 seropositive subjects.


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