✦ LIBER ✦
Persistence of Free HBV DNA in Body Secretions and Liver Despite Loss of Serum HBV DNA After Interferon-Induced Seroconversion
✍ Scribed by Elizabeth Ann Fagan; Graeme J. M. Alexander; Fergus Davison; Dr. Roger Williams
- Book ID
- 102376912
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 443 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0146-6615
No coin nor oath required. For personal study only.
✦ Synopsis
Following interferon therapy, a chronic hepatitis B (HBV) carrier lost all serum markers of active viral replication and became anti-HBe positive but remained positive for free and replicative HBV-DNA in semen, saliva, urine, and liver four months later. At 12 months, when he also developed anti-HBs, urine and saliva analysed for free HBV-DNA were positive. Despite histological remission and loss of HBV-DNA from serum, the potential for transmission of HBV and reactivation of disease remain.