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Persistence of E2A/PBX1 transcripts in t(1;19) childhood acute lymphoblastic leukemia: Correlation with chemotherapy intensity and clinical outcome

โœ Scribed by Carlo Lanza; Enrico Gottardi; Gianluca Gaidano; Claudia Vivenza; Adele Parziale; Fatima Perfetto; Marinella Fornaci; Elena Barisone; Enrico Madon; Giuseppe Basso; Giuseppe Saglio


Book ID
113240138
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
295 KB
Volume
20
Category
Article
ISSN
0145-2126

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The t(1;19)(q23;p13), detected cytogenetically in 5-6% of cases, is one of the most common translocations in childhood acute lymphoblastic leukemia (ALL). Most t(1;19)ฯฉ ALLs are pseudodiploid or contain fewer than 50 chromosomes, are classified as pre-B based on expression of cytoplasmic, but not su