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Peroxynitrite-mediated stress is associated with proliferation of human metastatic colorectal carcinoma in the liver

✍ Scribed by Shohei Kondo; Shinya Toyokuni; Tatsuaki Tsuruyama; Munetaka Ozeki; Tsuyoshi Tachibana; Michiko Echizenya; Hiroshi Hiai; Hisashi Onodera; Masayuki Imamura


Book ID
117467252
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
297 KB
Volume
179
Category
Article
ISSN
0304-3835

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## Abstract It has been previously demonstrated that human carcinomas express interleukin‐2 receptor (IL‐2R) α, β, and γ chains. The β and γ chains of IL‐2R have intermediate binding affinity for IL‐2 and are responsible for the intracellular signaling cascades after IL‐2 stimulation. IL‐2Rα lacks