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Peroxynitrite induces enterocyte p38 map kinase regulation of GADD45 expression

✍ Scribed by A. Young; A. Grishin; C. Leaphart; C. Wong; X. Zhang; H.R. Ford; J.S. Upperman

Book ID
116702368
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
58 KB
Volume
130
Category
Article
ISSN
0022-4804

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Bone resorption is glucose concentration dependent. Mechanisms regulating glucose-dependent increases in bone resorption have not been identified. Glucose activates p38 MAP-kinase in other cells and since MAP kinases activate transcription factors, we hypothesized that glucose-stimulated bone resorp