Peroxisome proliferators: mechanisms of adverse effects in rodents and molecular basis for species differences

PDGF-induced proliferation in human arte

PDGF-induced proliferation in human arterial and venous smooth muscle cells: Molecular basis for differential effects of PDGF isoforms

✍ Li Li; Donald K. Blumenthal; Christi M. Terry; Yuxia He; Mary L. Carlson; Alfred 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 735 KB

## Abstract Platelet‐derived growth factor (PDGF) has been implicated in the pathogenesis of arterial atherosclerosis and venous neointimal hyperplasia. We examined the effects of PDGF isoforms on smooth muscle cells (SMCs) from arterial and venous origins in order to further understand the differe