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Peroxisome proliferators and carcinogenesis: editorial perspectives

✍ Scribed by Russell C Cattley; Ruth A Roberts

Book ID
114072673
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
49 KB
Volume
448
Category
Article
ISSN
0027-5107

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Concern exists regarding peroxisome proliferator (PP) xenobiotic exposure because many PPs are potent hepatocarcinogens in rodents. The mechanism of carcinogenicity induced by PPs is atypical compared with those of other hepatocarcinogens in that the former appears to involve alterations in expressi