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Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

✍ Scribed by Yong-Xu Wang; Chih-Hao Lee; Sambath Tiep; Ruth T Yu; Jungyeob Ham; Heonjoong Kang; Ronald M Evans

Book ID
117269488
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
874 KB
Volume
113
Category
Article
ISSN
0092-8674

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Peroxisome-Proliferator-Activated Recept
Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity
✍ Yong-Xu Wang; Chih-Hao Lee; Sambath Tiep; Ruth T Yu; Jungyeob Ham; Heonjoong Kan 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 874 KB

In contrast to the well-established roles of PPARgamma and PPARalpha in lipid metabolism, little is known for PPARdelta in this process. We show here that targeted activation of PPARdelta in adipose tissue specifically induces expression of genes required for fatty acid oxidation and energy dissipat