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Peroxisome assembly in yeast

✍ Scribed by Marten Veenhuis; Jan A.K.W. Kiel; Ida J. Van der Klei


Book ID
102888456
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
520 KB
Volume
61
Category
Article
ISSN
1059-910X

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✦ Synopsis


Abstract

Peroxisomes are essential organelles that may be involved in various functions, dependent on organism, cell type, developmental stage of the cell, and the environment. Until recently, peroxisomes were viewed as a class of static organelles that developed by growth and fission from pre‐existing organelles. Recent observations have challenged this view by providing evidence that peroxisomes may be part of the endomembrane system and constitute a highly dynamic population of organelles that arises and is removed upon environmental demands. Additionally, evidence is now accumulating that peroxisomes may arise by alternative methods. This review summarizes relevant recent data on this subject. In addition, the progress in the understanding of the principles of the peroxisomal matrix protein import machinery is discussed. Microsc. Res. Tech. 61:139–150, 2003. Β© 2003 Wiley‐Liss, Inc.


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## Abstract In the last two decades, much progress has been made in understanding the process of induction and biogenesis of peroxisomes, essential organelles in all eukaryotes. Only relatively recently, the first molecular studies on the selective degradation of this important organelleβ€”a process