The observation that purified yeast glutamine synthetase is rapidly inactivated in a thiol-containing buffer yet retains activity in crude extracts containing the same thiol led to our discovery of an enzyme that protects against oxidation in a thiol-containing system. This novel antioxidant enzyme
โฆ LIBER โฆ
Peroxiredoxins: A historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling
โ Scribed by Sue Goo Rhee; Ho Zoon Chae; Kanghwa Kim
- Book ID
- 113629550
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 203 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0891-5849
No coin nor oath required. For personal study only.
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## Abstract The mechanism of action of ZR2002, a chimeric amino quinazoline designed to possess mixed EGFR tyrosine kinase (TK) inhibitory and DNA targeting properties, was compared to those of ZR01, a reversible inhibitor of the same class and PD168393, a known irreversible inhibitor of EGFR. ZR20