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Peroxiredoxin 6 deficiency and atherosclerosis susceptibility in mice: significance of genetic background for assessing atherosclerosis

✍ Scribed by Xiaosong Wang; Shelley A. Phelan; Christina Petros; Eric F. Taylor; Gerhard Ledinski; Günther Jürgens; Kristina Forsman-Semb; Beverly Paigen


Book ID
118420426
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
331 KB
Volume
177
Category
Article
ISSN
0021-9150

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We previously reported that mice have at least one major gene determining atherosclerosis susceptibility, Ath-1. Susceptible alleles of Ath-1 are found in strain C57BL/6J and are associated with relatively low levels of high-density lipoprotein cholesterol (HDL-C) when these mice are fed an atheroge