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Peroxidase-catalyzed covalent binding of the antitumor drug N2-methyl-9-hydroxyellipticinium to DNA in vitro

โœ Scribed by Auclair, Christian; Dugue, Bernard; Meunier, Bernard; Paoletti, Claude


Book ID
125941165
Publisher
American Chemical Society
Year
1986
Tongue
English
Weight
709 KB
Volume
25
Category
Article
ISSN
0006-2960

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Renal toxicity of the antitumor drug N2-
โœ G. Raguenez-Viotte; C. Dadoun; P. Buchet; T. Ducastelle; J. P. Fillastre ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 550 KB

Celiptium (N2-methyl-9-hydroxy-ellipticinium) is an antitumoral agent used to treat bone metastases from breast carcinomas. This new drug appeared to be of great interest because of the absence of hepato-or myelotoxicity. Three different investigators recently mentioned cases of celiptium-induced re