๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Peroperative evaluation of the viability of ischaemic colon in primates

โœ Scribed by A. R. Moossa; D. B. Skinner; C. K. Zarins; B. A. Rhodes

Publisher
John Wiley and Sons
Year
1974
Tongue
English
Weight
417 KB
Volume
61
Category
Article
ISSN
0007-1323

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โœฆ Synopsis

Abstract

An experimental model of ischaemic colitis was produced in 14 rhesus monkeys by complete vascular occlusion to the splenic flexure for periods varying from 4 to 8.5 hours. Clinical assessment of bowel viability following revascularization was inaccurate in 10 monkeys. Reactive hyperaemia was quantitatively measured using 99mtechnetium-tagged albumin micro-spheres and this correlated well with autopsy findings โ€“ a marked hyperaemic response suggested a transient form of ischaemic colitis; a diminished or absent hyperaemic response predicted the development of strictures or gangrene of the colon segment. A clinical trial is currently being organized to assess the viability of ischaemic bowel at laparotomy.

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