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Permissive Effect of Insulin-like Growth Factor I (IGF-I) on Gonadotropin Releasing-hormone Action on In Vitro Growth Hormone Release, in Rainbow Trout (Oncorhynchus mykiss)

✍ Scribed by O Blaise; P.-Y Le Bail; C Weil


Book ID
114215779
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
484 KB
Volume
116
Category
Article
ISSN
0300-9629

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## Abstract A recombinant human IGF‐I (rhIGF‐I) was applied to primary cultures of rainbow trout pituitary cells. In wells containing 3 Γ— 10^4^ and 6 Γ— 10^4^ cells/well, rhIGF‐I inhibited basal GH release both in short (6 h) and long (12 and 24 h) exposures. The decline in GH release was dose‐depen