Permeability properties of gels and membranes derived from chitosan

✍ Scribed by Hirano, Shigehiro ;Tobetto, Kenji ;Hasegawa, Masahiro ;Matsuda, Noriaki

• Publisher: John Wiley and Sons
• Year: 1980
• Tongue: English
• Weight: 420 KB
• Volume: 14
• Category: Article
• ISSN: 0021-9304
• DOI: 10.1002/jbm.820140414

✦ Synopsis

Abstract

A series of membranes was prepared by air‐drying the thin layers of N‐acyl‐ and N‐arylidene‐chitosan gels. Their flow rates of water and permeabilities of various compounds were examined. N‐Acylchitosan membranes were stable in both dilute acid and alkali, but N‐arylidene‐chitosan membranes were unstable in dilute acid. N‐Acetylchitosan membranes were stable in formic acid at room temperature for up to 7 hr. The flow rates of water through N‐acetylchitosan membranes were 10.0–23.6 × 10^−3^ ml/cm^2^ min under a pressure of 3 kg/cm^2^, and were unchanged by the membrane thickness (12–60 μm). The increase of carbon numbers for N‐acyl groups caused a slight decrease in the flow rates, and the flow rates were decreased by partial O‐acetylation of N‐acetylchitosan membranes. The flow rate of water through chitosan membranes (thickness 30–35 μm) was 7.1 × 10^−4^ ml/cm^2^ min, which was decreased by an increase in the membranes thickness. Low‐molecular‐weight compounds (MW < 2900) passed through these membranes, but high molecular‐weight compounds (MW > 13,000) did not pass through.