Permanent expression of midbrain dopaminergic neurons traits in differentiated amniotic epithelial cells
β Scribed by Hassan Niknejad; Tina Deihim; Abolhassan Ahmadiani; Masoumeh Jorjani; Habibollah Peirovi
- Book ID
- 116773693
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 808 KB
- Volume
- 506
- Category
- Article
- ISSN
- 0304-3940
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## Abstract Cells from human amniotic fluid derived from the fetus are considered a source of multipotent cells. Their properties have not been fully exploited, partially because unlike other embryonic sources such as embryonic stem (ES) cells, cell lines from amniocentesis samples have not been ge
Parkinson's disease is characterized by the progressive degeneration of midbrain dopaminergic neurons. Several studies have examined the effects of the dopaminergic neurotrophins growth/differentiation factor 5 (GDF5) and glial cell line-derived neurotrophic factor (GDNF) on these neurons in vitro.