Permanent alopecia following chemotherapy and bone marrow transplantation

✍ Scribed by D Tran; Rd Sinclair; Ap Schwarer; Cw Chow

• Book ID: 104468988
• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 142 KB
• Volume: 41
• Category: Article
• ISSN: 0004-8380
• DOI: 10.1046/j.1440-0960.2000.00405.x

✦ Synopsis

SUMMARY

Alopecia can be a psychologically daunting prospect for people requiring cancer chemotherapy. Fortunately, most patients experience only temporary hair loss. We report the case of a 23‐year‐old woman with chronic myeloid leukaemia who developed permanent, near‐total alopecia of her scalp, eyebrows, eyelashes, axillary and pubic hair following busulphan and cyclophosphamide chemotherapy which was used as conditioning prior to allogeneic bone marrow transplantation. The histology from a scalp biopsy revealed hair follicle destruction. Topical minoxidil failed to induce significant re‐growth.