Perivascular delivery of heparin regulates myointimal hyperplasia

Local delivery of c-myc neutrally charge

Local delivery of c-myc neutrally charged antisense oligonucleotides with transport catheter inhibits myointimal hyperplasia and positively affects vascular remodeling in the rabbit balloon injury model

✍ Nicholas Kipshidze; Eamon Keane; David Stein; Paramjith Chawla; Victor Skrinska; 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 592 KB

## Abstract Myointimal hyperplasia after percutaneous transluminal coronary angioplasty (PTCA) is a key component of the process of restenosis. The c‐myc is a critical cell‐cycle division protein involved in the formation of neointima. We evaluated the long‐term impact of local delivery of c‐myc ne