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Perivascular delivery of heparin for the reduction of smooth muscle cell proliferation after endothelial injury

✍ Scribed by D. Teomim; I. Fishbien; G. Golomb; L. Orloff; M. Mayberg; A.J. Domb


Book ID
114163774
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
865 KB
Volume
60
Category
Article
ISSN
0168-3659

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It has been reported previously that systemic application of low molecular weight heparin (LMWH) suppresses smooth muscle cell (SMC) proliferation after balloon angioplasty in experimental studies. However, the high concentration of heparin required for a beneficial effect may cause severe bleeding