Peritonitis induces the synthesis of 1α,25-dihydroxyvitamin D3 in macrophages from CAPD patients
✍ Scribed by M.E. Hayes; D.J. O'Donoghue; F.W. Ballardie; E.B. Mawer
- Book ID
- 115919559
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 222 KB
- Volume
- 220
- Category
- Article
- ISSN
- 0014-5793
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Cultured microglial cells were examined for their ability to metabolize 25-hydroxyvitamin D, (25-(OH) D,). Upon exposure to lipopolysaccharide, microglial cells produced a vitamin D metabolite which comigrated with synthetic 1,25-dihydroxyvitamin D, (1,25-(OH),D,) in two different systems of high pe