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Peripherally Selective Diphenyl Purine Antagonist of the CB1 Receptor

✍ Scribed by Fulp, Alan; Bortoff, Katherine; Zhang, Yanan; Snyder, Rodney; Fennell, Tim; Marusich, Julie A.; Wiley, Jenny L.; Seltzman, Herbert; Maitra, Rangan


Book ID
121249897
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
269 KB
Volume
56
Category
Article
ISSN
0022-2623

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## Abstract During immune‐mediated demyelinating lesions, the endocannabinoid system is involved in the pathogenesis of both neuroinflammation and neurodegeneration through different mechanisms. Here we explored the cellular distribution of the CB1 receptor (CB1R) in the central nervous system (CNS