𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Peripheral T-cell lymphomas, unspecified (or not otherwise specified): a review

✍ Scribed by Delvys Rodriguez-Abreu; Volmar Belisario Filho; Emanuele Zucca

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
206 KB
Volume
26
Category
Article
ISSN
0278-0232

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Peripheral T‐cell lymphomas (PTCL) comprises a heterogeneous group of haematological tumours, which originate from mature T‐cells, and constitute less than 15% of all non‐Hodgkin's lymphomas (NHLs) in adults. The current WHO classification recognizes nine distinct clinicopathologic peripheral T‐cell NHLs, being the ‘unspecified variant’ (PTCL‐U) the most common subtype. These neoplasms often present in advanced stage at diagnosis, and most commonly have an aggressive clinical course requiring prompt treatment. The rarity of these tumours requires additional studies to better understand their biology and search for new therapies which may hopefully improve the dismal outcome of most patients. This review aims to describe the pathobiological aspects as well the clinical characteristics and current therapeutic strategies of the PTCLs, with special attention to the group of PTCL‐U Copyright © 2007 John Wiley & Sons, Ltd.

📜 SIMILAR VOLUMES

Striking morphology of leukemic phase of
Striking morphology of leukemic phase of childhood peripheral T-cell lymphoma, not otherwise specified
✍ Anita Chopra; Rajive Kumar; Rachna Seth; Mona Anand; Ruma Ray 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 162 KB 👁 1 views

Leukemic phase of childhood peripheral T-cell lymphoma, not otherwise specified is rare [1] and is even more uncommon in children. The purpose of this communication is to record the very striking morphology of this entity that we saw in a 7-year-old child who presented with fever, features of superi

Chromosomal aberrations in angioimmunobl
Chromosomal aberrations in angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma unspecified: A matrix-based CGH approach
✍ Christoph Thorns; Boris Bastian; Daniel Pinkel; Ritu Roydasgupta; Jane Fridlyand 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB

## Abstract Angioimmunoblastic T‐cell lymphoma (AILT) is a histopathologically well‐defined entity. However, despite a number of cytogenetic studies, the genetic basis of this lymphoma entity is not clear. Moreover, there is an overlap to some cases of peripheral T‐cell lymphoma unspecified (PTCL‐u

Clinical relevance of immunophenotype in
Clinical relevance of immunophenotype in a retrospective comparative study of 297 peripheral T-cell lymphomas, unspecified, and 496 diffuse large B-cell lymphomas : Experience of the Intergruppo Italiano Linfomi
✍ Fortunato Morabito; Andrea Gallamini; Caterina Stelitano; Vincenzo Callea; Cesar 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB

## Abstract ## BACKGROUND To assess the impact of T‐cell/B‐cell phenotype on clinical outcome, the authors retrospectively compared patients who had peripheral T‐cell lymphoma, unspecified (PTCL‐U), with patients who had diffuse large B‐cell lymphoma (DLBCL). ## METHODS Two hundred ninety‐seven

Peripheral T-cell lymphoma presenting as
Peripheral T-cell lymphoma presenting as ascites: A case report and review of the literature
✍ Funda Vakar-López; Mary Yang 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 87 KB 👁 2 views

Here we report an unusual case of T-cell lymphoma presenting as ascites. A 49-yr-old woman was admitted to the hospital for abdominal discomfort associated with increasing abdominal girth over the course of 3 mo. She also complained of nausea, vomiting, and diarrhea. On physical examination, a tense