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Peripheral opiate receptors are not involved in the naloxone-sensitive cardiovascular effects of clonidine in rats

✍ Scribed by Rogelio Mosqueda-Garcia; George Kunos


Book ID
115798900
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
541 KB
Volume
442
Category
Article
ISSN
0006-8993

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The hypothesis that the antinociceptive effects of pentazocine, a mixed agonist-antagonist opiate of the benzomorphan class, are mediated by a dual opiate-dopaminergic mechanism was tested using a two-choice procedure in which rats were required to discriminate the presence or absence of shock. The