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Peripheral nerve stimulation during MRI: Effects of high gradient amplitudes and switching rates

✍ Scribed by C. L. G. Ham; J. M. L. Engels; G. T. van de Wiel; A. Machielsen


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
501 KB
Volume
7
Category
Article
ISSN
1053-1807

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✦ Synopsis


Abstract

The application of high gradient amplitudes and switching rates for MRI and spectroscopy, resulting in short rise times for the gradient field and high changes of the magnetic flux density in the patient, is known to possibly evoke peripheral nerve stimulation (PNS) in patients. These effects have been studied on 20 volunteers under different experimental circumstances. The results of these measurements are partially in line with earlier findings reported in the literature. New information is found for the dependence of the PNS threshold level as a function of the rise time of the gradient waveform. The PNS threshold level, expressed in terms of dB/dt, is found to be proportional with t^−05^, where t is the switch time for the gradients. Indications are found that |B|, the modulus of the gradient vector field, is more closely related to the PNS threshold level than B~z~, the imaging component of the gradient field. From the experiments, it is furthermore concluded that only for the imaging protocols characterized by the application of long bipolar repetitive gradient pulse trains, such as echo‐planar imaging, PNS is expected at the reported threshold levels. For the protocols based on spin echo, turbo spin echo, inversion recovery, fast field echo, etc., characterized by shorter gradient pulse trains, the threshold levels are expected to be much higher.


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## Abstract ## Purpose: To compare thresholds for peripheral nerve stimulation from gradient switching in whole body magnetic resonance (MR) equipment of different design. ## Materials and Methods: Threshold data obtained in three experiments were reformatted into a single joint data set describ