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Peripheral nerve responses during ischemia in the evaluation of diabetic neuropathy

✍ Scribed by Dr. Steven H. Horowitz; Fredda Ginsberg-Fellner


Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
302 KB
Volume
1
Category
Article
ISSN
0148-639X

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✦ Synopsis


Abstract

The stability of sensory conduction and evoked potentials during ischemia has been used in the evaluation of diabetic neuropathy and diabetic control (Hgb A~1~C). Six newly diagnosed juvenile diabetics were studied at diagnosis and 3 to 12 months later. In three patients in good control, ischemic β€œresistance” became normal. In three patients in poor control, resistance remained increased; two of these three experienced a 10%–20% slowing in conduction velocity. Similar relationships between control and ischemic resistance are found in long‐term diabetics. These data suggest that abnormal ischemic resistance may herald the onset of an electrical and clinical neuropathic state.


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Peripheral nerve dysfunction is reflecte
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Peripheral nerves contain both autonomic and so-type of diabetes [insulin-dependent diabetes mellitus (IDDM) versus non-insulin-dependent diabetes mel-matic fibers. Autonomic and peripheral sensory neuropathy may therefore be regarded as manifestations litus (NIDDM)]. of a general diabetic polyneuro