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Peripheral Nerve Regeneration in CNTF Knockout Mice

โœ Scribed by Mike Yao; Melinda S. Moir; Michelle Z. Wang; Michael P. To; David J. Terris

Book ID
110082045
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
639 KB
Volume
109
Category
Article
ISSN
0023-852X

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๐Ÿ“œ SIMILAR VOLUMES

Delay of CNTF decrease following periphe
Delay of CNTF decrease following peripheral nerve injury in C57BL/Wld mice
โœ M.C. Subang; M.A. Bisby; P.M. Richardson ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 115 KB

In peripheral nerves, ciliary neurotrophic factor (CNTF) is localized to a subset of Schwann cells and is decreased in synthesis during Wallerian degeneration. This pattern of expression is similar to that of myelin protein genes. In the present study, C57BL/Wld mice, which exhibit delayed Wallerian

Peripheral nerve injury down-regulates C
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โœ E. D. Rabinovsky; G. M. Smith; D. P. Browder; H. D. Shine; Dr. J. L. McManaman ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 538 KB

Ciliary neurotrophic factor (CNTF) is a 200-amino acid protein expressed in high concentrations by peripheral nerves and is thought to be important for the survival and regeneration of injured motoneurons (Lin et al., J Biol Chem 26589424947, 1990). To better understand CNTF's role in nerve injury w

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Following peripheral nerve injury, cholesterol from degenerating myelin is retained locally within macrophages and subsequently reutilized by Schwann cells for synthesis of new myelin during nerve regeneration. Substantial evidence indicates this conservation and reutilization of cholesterol is acco