Since the natural history of hepatitis C virusassociated liver disease and the therapeutic responsiveness might vary according to liver and blood mononuclear cells viral levels, it may be important to quantitate viral RNA in liver, blood mononuclear cells and serum, and to compare these data with ge
Peripheral mononuclear cells of haemophiliacs with chronic liver disease are infected with replicating hepatitis C virus
β Scribed by Christine Henin; Mike Makris; Julie Brown; Ian R. Peake; Eric F. Preston
- Book ID
- 114713700
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 274 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0007-1048
No coin nor oath required. For personal study only.
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## Abstract The mechanisms underlying chronicity of hepatitis C virus (HCV) infection are poorly understood, but the importance of impaired viral clearance by the immune system has been suggested. The prevalence of HCV infection of peripheral blood mononuclear cells (PBMC) was in investigated in 34
## Abstract Hemophiliacs who have been exposed to unbeaten and/or dry heated pooled clotting factor concentrates are at high risk of chronic hepatitis C. Although the mechanism and site of hepatitis C virus (HCV) replication are not yet known, HCV is thought to replicate through a complementary neg