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Peripheral CD4+ T cells showing a Th2 phenotype in a patient with Mikulicz's disease associated with lymphadenopathy and pleural effusion

✍ Scribed by Katsuhisa Miyake; Masafumi Moriyama; Kumiko Aizawa; Shuji Nagano; Yasushi Inoue; Atsushi Sadanaga; Hitoshi Nakashima; Seiji Nakamura


Publisher
Springer
Year
2007
Tongue
English
Weight
300 KB
Volume
18
Category
Article
ISSN
1439-7595

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## Abstract Immunosuppressive CD4+CD25^hi^FoxP3+ T cells (T~reg~ cells) have been found at increased densities within the tumor microenvironment in many malignancies and interfere with protective antitumor immune responses. Osseous Ewing sarcomas (ESs) are thought to derive from a bone marrow (BM)