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Peripheral blood mononuclear cell proliferative responses to soluble and particulate heat shock protein 65 in health and inflammatory bowel disease

✍ Scribed by L. C. Pele; S. J. Thompson; B. Kirkham; R. P. H. Thompson; J. J. Powell

Publisher: SP Birkhäuser Verlag Basel
Year: 2007
Tongue: English
Weight: 149 KB
Volume: 56
Category: Article
ISSN: 1420-908X
DOI: 10.1007/s00011-006-6136-5

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## Abstract Recent evidence has pointed to the mycobacterial 65‐kDa heat‐shock protein (hsp 65) as an antigen that may be important in the pathogenesis of rheumatoid arthritis (RA). Using limiting dilution analysis the frequency of purified protein derivative of tuberculin (PPD) and hsp 65‐responsi