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Peripheral blood monocytes derived dendritic cells generated with interferon-α and granulocyte-macrophage colony-stimulating factor are potent IL-12 producers

✍ Scribed by Shinichi Egawa; Robbie Mailliard; Michael T Lotze


Book ID
114353848
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
147 KB
Volume
191
Category
Article
ISSN
1072-7515

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We evaluated the effects of interleukin (IL)-10 on the differentiation of dendritic cells (DC) obtained by culturing plastic-adherent peripheral blood mononuclear cells for 7 days in presence of granulocyte/macrophage-colony-stimulating factor (GM-CSF) + IL-4. The addition of IL-10 at the initiation