Peripheral blood and synovial fluid monocyte activation in inflammatory arthritis. i. a cytofluorographic study of monocyte differentiation antigens and class ii antigens and their regulation by γgm-interferon

Peripheral blood and synovial fluid mono

Peripheral blood and synovial fluid monocyte activation in inflammatory arthritis. ii. low levels of synovial fluid and synovial tissue interferon suggest that γgm-interferon is not the primary macrophage activating factor

✍ Gary S. Firestein; Nathan J. Zvaifler 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 763 KB

Because synovial fluid monocytes (SFM) in patients with inflammatory arthritis bear an activated phenotype (i.e., high expression of HLA-DR and low expression of the monocyte differentiation antigen Mo2), we assessed the role of gamma-interferon (gamma-IFN) in the activation of these cells. Sensitiv