𝔖 Bobbio Scriptorium
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Peripheral B cell selection and homeostasis

✍ Scribed by Michael P. Cancro; Susan Harless Smith


Book ID
111639162
Publisher
Springer-Verlag
Year
2003
Tongue
English
Weight
149 KB
Volume
27
Category
Article
ISSN
0257-277X

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The B-lymphocyte repertoire can be divided into a primary repertoire of virgin B cells and a secondary repertoire of antigenically experienced cells. Self-tolerance requires that neither of these repertoires contains potentially active cells capable of high-affinity, anti-self antibody production. R