✦ LIBER ✦

Perinatal transmission of hepatitis B virus in Kenya: Its relation to the presence of serum HBV-DNA and Anti-HBe in the mother

✍ Scribed by C. Greenfield; V. Osidiana; P. Karayiannis; S. Galpin; R. Musoke; T. P. Jowett; P. Mati; P. M. Tukei; Professor H. C. Thomas

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 487 KB
Volume: 19
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890190205

No coin nor oath required. For personal study only.

✦ Synopsis

In Kenya hepatitis B virus (HBV) infection and its sequelae are common. We followed up 49 hepatitis B surface antigen (HBsAg)-positive mothers and their newborn infants for 9 months to determine the importance of perinatal transmission in the African and to relate this to the HBe and HBV-DNA status of the mother. Our study shows that perinatal transmission is relatively unimportant in Kenya and that this may be a consequence of the low levels of circulating HBV-DNA in the maternal plasma. These results imply that vaccination without hyperimmune globulin may be adequate to control HBV infection in Kenya.

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