Adult T-cell leukernidlymphoma (ATL), a malignancy of mature CDCpositive lymphocytes, has been etiologically linked to the human retrovirus HTLV-I. Although a long latent period is suggested from migrant studies, little prospective information on the risk of developing ATL among persons with HTLV-I
Perinatal infection of human T-lymphotropic virus type I, the etiologic virus of adult T-cell leukemia/lymphoma. DNA amplification of specific human T-lymphotropic virus type I sequences
β Scribed by Fumitaka Saji; Kazutomo Ohashi; Yoshihiro Tokugawa; Shoji Kamiura; Chihiro Azuma; Osamu Tanizawa
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 543 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0008-543X
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## Objective. To clarify the involvement of human T lymphotropic virus type I (HTLV-I) in the pathogenesis of Sjogren's syndrome (SS). Methods. In HTLV-I-seropositive patients with SS, HTLV-I proviral DNA in the labial salivary glands (SG) was detected by polymerase chain reaction (PCR) amplificat
Human T-cell lymphotropic virus type-I (HTLV-I) is the etiologic agent of HTLV-I-associated myelopathy/tropical spastic paraparesis (HAMTTSP) and adult T-cell leukemia (ATL). HAMFSP and ATL occur infrequently among HTLV-I-infected individuals, and rarely develop in the same individual. To study host