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Perinatal exposure to 60-Hz electric fields: Effects on the development of the visual-evoked response in rats

โœ Scribed by R. A. Jaffe; C. A. Lopresti; D. B. Carr; R. D. Phillips

Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
709 KB
Volume
4
Category
Article
ISSN
0197-8462

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โœฆ Synopsis

Two independent series of experiments were performed on 114 male Sprague-Dawleyderived, albino rat pups, which represented 61 litters in experimental series I and 53 litters in experimental series 11. Animals were exposed for 20 h/day from conception to testing (postnatal days 11-20) to a vertical, 65-kV/m, 60-Hz electric field or sham-exposed.

Recordings of the visual-evoked response (VER) were obtained using a small silver ball elcctrode placed epidurally over the visual cortex. Visual stimuli consisted of 10-ps light flashes delivered at 0.2 Hz. Computer-averaged VERs were obtained and power spectral analyses (fast Fourier transform) were performed on the tapered (split cosine-bell window), averaged VERs. The expected age-related changes were clearly evident; however, a detailed analysis of VER component latencies, peak-to-peak amplitude, and power spectra failed to reveal any consistent, statistically significant effect of exposure to 60-Hz electric fields.

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