Perinatal changes in epidermal innervation in rat and mouse

✍ Scribed by M. J. T. Fitzgerald

• Book ID: 102112705
• Publisher: John Wiley and Sons
• Year: 1966
• Tongue: English
• Weight: 406 KB
• Volume: 126
• Category: Article
• ISSN: 0021-9967
• DOI: 10.1002/cne.901260103

✦ Synopsis

The development of cutaneous innervation in the rat and the mouse has been studied by silver techniques. In particular, the innervation patterns of adult and of perinatal skin have been compared. From the second prenatal day until the sixth postnatal day, the relatively thick epidermis is freely penetrated by nerve fibers; thereafter, the nerve endings appear to be confined to the dermis. The intraepidermal axans are directed obliquely, with a rough (and not exact) correspondence to the plane of future emergence of the hair shafts. The appearance of a transitory intra-epidermal innervation in rodent hairy skin is interpreted in the light of the development of intra-epidermal nerves elsewhere.