Periconceptional supplementation with folic acid: Does it prevent neural tube defects?
β Scribed by Patricia Aikins Murphy
- Book ID
- 103501634
- Publisher
- Elsevier Science
- Year
- 1992
- Weight
- 647 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0091-2182
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## Abstract ## BACKGROUND: It is well established that women who have had a pregnancy affected by a neural tube defect (NTD) have an elevated risk of a subsequent NTDβaffected pregnancy and that a high dose (4 mg/day) of folic acid taken around the time of conception prevents most recurrences of N
## Abstract The pioneering studies of Smithells et al. showed the reduction of recurrent neuralβtube defects (NTD) after periconceptional folic acidβcontaining multivitamin supplementation. The Hungarian Periconceptional Service was established in 1984, and this primary health care system offered a