Periconceptional intake of vitamin supplements and risk of multiple congenital anomalies
β Scribed by Shaw, Gary M. ;Croen, Lisa A. ;Todoroff, Karen ;Tolarova, Marie M.
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 83 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0148-7299
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## Abstract ## BACKGROUND Few inquiries into periconceptional nutrition, other than folate, and risk of heart defects exist. We investigated the observed association between conotruncal heart defects and periconceptional vitamin use, as well as potential associations with other dietary nutrients.
## Abstract Two previous Hungarian intervention trials showed that periconceptional folic acidβcontaining multivitamin supplementation did not change the total (birthβ+βfetal) prevalence of cases with multiple congenital abnormalities (MCAs). However, two US observational studies found an elevated