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Pericellular proteolysis by leukocytes and tumor cells on substrates: focal activation and the role of urokinase-type plasminogen activator

✍ Scribed by AndreiL. Kindzelskii; Imran Amhad; Donald Keller; M.-J. Zhou; RichardP. Haugland; B.A. Garni-Wagner; MargaretR. Gyetko; RobertF. Todd; HowardR. Petty


Book ID
106099565
Publisher
Springer
Year
2004
Tongue
English
Weight
397 KB
Volume
121
Category
Article
ISSN
1432-119X

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## Abstract The urokinase‐type plasminogen activator receptor (uPAR, CD87) plays a central role in the plasminogen activation cascade, which participates in extracellular matrix degradation, cell migration and invasion. Here we performed a comprehensive immmunohistochemical evaluation of uPAR expre