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Pericardial effusion with cardiac tamponade as a cardiac manifestation of duchenne muscular dystrophy

✍ Scribed by Jainn-Jim Lin; Mao-Sheng Hwang; Shao-Hsuan Hsia; Hung-Tao Chung; Yu-Sheng Chang; Kuang-Lin Lin

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
158 KB
Volume
40
Category
Article
ISSN
0148-639X

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✦ Synopsis

Abstract

Duchenne muscular dystrophy (DMD) is the most common hereditary neuromuscular disease in children. It is an X‐linked hereditary dystrophinopathy due to the absence of dystrophin. Its onset is often in early childhood and presents with proximal distribution of weakness and a progressive course. Cardiac involvement in DMD is common, and its onset is usually after the age of 10 years. The most common cardiac manifestations are a dilated cardiomyopathy and cardiac arrhythmia. However, pericardial effusion with cardiac tamponade is a very rare cardiac complication of DMD. We report a boy with DMD who initially presented with progressive dyspnea and an enlarged cardiac silhouette on chest radiography who subsequently developed a large pericardial effusion with cardiac tamponade. Early recognition of pericardial effusion with cardiac tamponade is important for institution appropriate therapy. Muscle Nerve, 2009

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