Perfusion bioreactor system for human mesenchymal stem cell tissue engineering: Dynamic cell seeding and construct development

Effects of shear stress on 3-D human mes

Effects of shear stress on 3-D human mesenchymal stem cell construct development in a perfusion bioreactor system: Experiments and hydrodynamic modeling

✍ Feng Zhao; Ravindran Chella; Teng Ma 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 264 KB 👁 1 views

## Abstract Shear stress is an important biomechanical parameter in regulating human mesenchymal stem cell (hMSC) construct development. In this study, the biomechanical characteristics of hMSCs within highly porous 3‐D poly (ethylene terephthalate) (PET) matrices in a perfusion bioreactor system w