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Perforin enhances the granulysin-induced lysis of Listeria innocua in human dendritic cells

✍ Scribed by Michael Walch; Sonja Latinovic-Golic; Ana Velic; Hanna Sundstrom; Claudia Dumrese; Carsten A Wagner; Peter Groscurth; Urs Ziegler


Book ID
115005105
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
589 KB
Volume
8
Category
Article
ISSN
1471-2172

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## Abstract RNA interference technology has been used to modulate dendritic cell (DC) function by targeting the expression of genes such as IL‐12 and NF‐kB. In this paper, we demonstrate that transfectionof DC with IL‐10‐specific double strands of small interference RNA (siRNA) resulted in potent s