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Perforation of the oesophagus

✍ Scribed by James D. R. Rose; Paul M. Smith; J. G. Banks; J. Bancewicz

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
149 KB
Volume
69
Category
Article
ISSN
0007-1323

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✦ Synopsis

The importance of the syi drome lies in the Fact that this seems to be one of the first groups of patients where definable abnormalities in the coagulation and fibrinolytic systems correlate with the development of venous thrombosis. One such patient who survived an episode of mesenteric venous thrombosis which was treated by thrombectomy had a defect in his fibrinolytic system (3) and another had a low level of antithrombin 111 (4). We suspect that Casr 1 in Cam and Jamison's paper fits into the syndrome and it would be worth while seeing if either of these hypercoagulable states are demonstrable in the patient. Long term anticoagulants may be indicated in symptomatic patients with antithrombin 111 deficiency (which tends to be familial) and the fibrinolytic defect can also be corrected with drugs (5).

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