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‘Perforated patch recording’ allows long-term monitoring of metabolite-induced electrical activity and voltage-dependent Ca2+ currents in pancreatic islet B cells

✍ Scribed by Lee C. Falke; Kevin D. Gillis; David M. Pressel; Stanley Misler

Book ID: 115922513
Publisher: Elsevier Science
Year: 1989
Tongue: English
Weight: 495 KB
Volume: 251
Category: Article
ISSN: 0014-5793
DOI: 10.1016/0014-5793(89)81448-6

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Low concentrations of tetraethylammonium chloride (TEA), which inhibit voltage-and Ca2+-sensitive K § channels (K § channels), were used to investigate whether these channels play a role in the control of glucoseinduced electrical activity (slow waves with spikes) in mouse pancreatic B-cells. Additi