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Percutaneous Absorption of Clindamycin in the Pig and the Rat

โœ Scribed by J. E. Gray; K. Stern; R. Weaver; E. R. Larsen; F. Newman; C. M. Metzler


Book ID
110875032
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
305 KB
Volume
22
Category
Article
ISSN
0011-9059

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Metabolism of clindamycin I: Absorption
โœ F. F. Sun; R. S. P. Hsi ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 534 KB

Clindamycin hydrochloride, randomly labeled with tritium, was synthesized and used for animal metabolism studies. The drug was administered to rats (oral and intraperitoneal routes) and dogs (oral and intramuscular routes) at a dose of 50-150 mg./ kg. In both species, after the oral or parenteral dr