Peracetic acid as a superior oxidant for preparation of [123I]IBZM: A potential dopamine D-2 receptor imaging agent

6-[123I]Iodo-2-[[4-(2-methoxyphenyl) pip

6-[123I]Iodo-2-[[4-(2-methoxyphenyl) piperazin-1-yl]methyl]imidazo[1,2-a]pyridine as potential SPECT agent for imaging dopamine D4 receptor: synthesis and in vivo evaluation in a nonhuman primate

✍ David Alagille; Andrei O. Koren; Greg Kudej; Julie Staley; Kelly Cosgrove; John 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 129 KB 👁 1 views

## Abstract The dopamine D~4~ receptor subtype has drawn considerable attention due to its potential implication in schizophrenia and erectile dysfunction. 6‐[^123^I]Iodo‐2‐[[4‐(2‐methoxyphenyl)piperazin‐1‐yl]methyl]imidazo[1,2‐__a__]pyridine [^123^I]‐1, a potent and selective new dopamine D~4~ ago