## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Peptidomimetics and Peptide Backbone Modifications
β Scribed by Jung-Mo Ahn; Nicholas A. Boyle; Mary T. MacDonald; Kim D. Janda
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 50 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
Reducing a CO to a CH 2 moiety in a peptide bond destroys the ability of the peptide link to act as a proton acceptor in a hydrogen-bonded structure. Here, this modification is introduced into different positions of the helical peptide, acetyl-WGG(RAAAA) 4 R-amide, and the melting of these peptides
## Abstract For Abstract see ChemInform Abstract in Full Text.
Novel 5-ring heterocyclic building blocks are synthesized. These can be incorporated into analogs of peptide antibiotics such as microcin B17, which is a potent DNA-gyrase inhibitor that exhibits eight thiazole and oxazole moieties. In particular, the syntheses of imidazole and bisoxazole amino acid