✦ LIBER ✦

Peptidomimetic inhibitors of p21ras farnesyltransferase: Hydrophobic functionalization leads to disruption of p21ras membrane association in whole cells

✍ Scribed by Yimin Qian; Michelle A. Blaskovich; Churl-Min Seong; Andreas Vogt; Andrew D. Hamilton; Said M. Sebti

Book ID: 108476895
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 404 KB
Volume: 4
Category: Article
ISSN: 0960-894X
DOI: 10.1016/s0960-894x(01)80287-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Effects of the farnesyltransferase inhib

Effects of the farnesyltransferase inhibitor UCF-1C/manumycin on growth and p21-ras post-translational processing in NIH3T3 cells

✍ Patricia Servais; Béatrice Gulbis; Dominique Fokan; Paul Galand 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 245 KB 👁 2 views

Examination of the effect of the farnesylprotein transferase (FPTase) inhibitor UCF1-C/manumycin on NIH3T3 cells transfected with a normal N-ras gene and expressing high levels of the corresponding p21-ras protein showed that 10 m UCF1-C immediately and reversibly inhibited growth in these cells, wi

G-Protein-Mediated Signaling in Choleste

G-Protein-Mediated Signaling in Cholesterol-Enriched Arterial Smooth Muscle Cells. 1. Reduced Membrane-Associated G-Protein Content Due to Diminished Isoprenylation of G-γ Subunits and p21ras †

✍ Pomerantz, Kenneth B.; Lander, Harry M.; Summers, Barbara; Robishaw, Janet D.; B 📂 Article 📅 1997 🏛 American Chemical Society 🌐 English ⚖ 256 KB

Expression of val-12 mutant RAS P21 in a

Expression of val-12 mutant RAS P21 in an IL-3-dependent murine myeloid cell line is associated with loss of serum-dependence and increases in membrane PIP2-specific phospholipase C activity

✍ Maria Teresa Rizzo; H. Scott Boswell; Denis English; Theodore G. Gabig 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 623 KB